H-Index 13. ORCID 0000-0002-9949-1983


  • Gibson D.A., Esnal-Zufiaurre A., Bajo-Santos C., Collins F., Critchley H.O.D., Saunders P.T.K. Profiling the expression and function of ER46 in human endometrial tissues and uterine NK cells. Human Reproduction Volume 35, Issue 3, March 2020.

  • Bain C.C., Gibson D.A., Steers N., Boufea K., Louwe P.A., Docherty C., Huici V., Gentek R., Magalhaes-Pinto M., Bajenoff M., Benezech C., Dockrell D., Saunders P.T.K., Batada N., Jenkins S.J. Origin and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages. bioRxiv 837336 doi:

  • Collins F., Itani N, Esnal-Zufiaurre A., Gibson D.A., Fitzgerald C., Saunders P.T.K. The ERβ5 splice variant increases oestrogen responsiveness of ERαpos Ishikawa cells. Endocr Relat Cancer. 2020 Feb;27(2):55-66. doi: 10.1530/ERC-19-0291.


  • Selective androgen receptor modulators (SARMs) have specific impacts on the mouse uterus. Simitsidellis I, Esnal Zufiaurre A., Kelepouri O., O'Flaherty E., Gibson D.A., Saunders P.T. J Endocrinol. 2019 Sep;242(3):227-239. doi: 10.1530/JOE-19-0153.


  • Gibson, D.A., Foster, P.A., Simitsidellis, I., Critchley, H.O.D., Kelepouri, O., Collins, F., Saunders, P.T.K. A Role for Steroid Sulfatase in Intracrine Regulation of Endometrial Decidualisation. Journal of Molecular Endocrinology, 2018. doi: 10.1530/JME-18-0037

  • Piccinato, C., Malvezzi. H., Gibson, D.A. , Saunders, P.T.K. Contribution of intracrine oestrogens to the etiology of endometriosis. Journal of Molecular Endocrinology, 2018.

  • Simitsidellis, I., Gibson, D.A. , Saunders, P.T.K. Animal models of endometriosis: Replicating the aetiology and symptoms of the human disorder. Best Practice & Research Clinical Endocrinology & Metabolism, 2018. doi: 10.1016/j.beem.2018.03.004.

  • Gibson, D.A., Saunders, P.T.K., McEwan, I.J. Androgens and androgen receptor: Above and beyond. Molecular and Cellular Endocrinology, 2018, 465, pp. 1-3. doi: 10.1016/j.mce.2018.02.013

  • Simitsidellis, I., Saunders, P.T.K., Gibson, D.A., Androgens and endometrium: New insights and new targets. Molecular and Cellular Endocrinology. 2018, 465, pp. 48-60. doi: 10.1016/j.mce.2017.09.022.

  • Gibson, D.A., Collins, F., Cousins, F.L., Esnal Zufiaurre, A., Saunders, P.T.K. The impact of 27-hydroxycholesterol on endometrial cancer proliferation. Endocrine-Related Cancer, 2018, 25 (4), pp. 381-391. doi: 10.1530/ERC-17-0449.

    • Awarded best poster prize at the nuclear receptors 2018 meeting and the Pfizer Award in 2017. Cover of Journal September 2018

  • Gibson, D.A., Simitsidellis, I., Kelepouri, O., Critchley, H.O.D., Saunders, P.T.K. Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age. Fertility and Sterility, 2018. doi: 10.1016/j.fertnstert.2017.12.024.

    • International press coverage and across the UK including interview with the Daily Mail. Altmetric score 159. Editorial commisioned by journal.


  • Giakoumelou, S., Wheelhouse, N., Brown, J., Wade, J., Simitsidellis, I., Gibson, D.A., Saunders, P.T.K., Horner, P., Entrican, G., Howie, S.E.M., Horne, A.W. Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release. Scientific Reports, 2018, 7 (1), art. no. 2001.


  • Cousins, F.L., Kirkwood, P.M., Saunders, P.T.K., Gibson, D.A. Evidence for a dynamic role for mononuclear phagocytes during endometrial repair and remodelling. Scientific Reports, 2016, 6, art. no. 36748.

    • Using transgenic reporter mice we developed complimentary flow cytometry and immunohistochemistry approaches to identify distinct populations of mononuclear phagocytes that associated with functionally discrete regions of repair and remodeling.

  • Cousins, F.L., Kirkwood, P.M., Murray, A.A., Collins, F., Gibson, D.A., Saunders, P.T.K. Androgens regulate scarless repair of the endometrial "wound" in a mouse model of menstruation. FASEB Journal, 2016 30 (8), pp. 2802-2811.

  • Gibson, D.A., Simitsidellis, I., Saunders, P.T.K. Regulation of androgen action during establishment of pregnancy. Journal of Molecular Endocrinology, 2016, 57 (1), pp. R35-R47.

  • Walters, K.A., Simanainen, U., Gibson, D.A. Androgen action in female reproductive physiology. Current Opinion in Endocrinology, Diabetes and Obesity, 2016, 23 (3), pp. 291-296.

  • Simitsidellis, I., Gibson, D.A., Cousins, F.L., Esnal-Zufiaurre, A., Saunders, P.T.K. A role for androgens in epithelial proliferation and formation of glands in the mouse uterus. Endocrinology, 2016, 157 (5), pp. 2116-2128.

  • Gibson, D.A., Simitsidellis, I., Cousins, F.L., Critchley, H.O.D., Saunders, P.T.K. Intracrine Androgens Enhance Decidualization and Modulate Expression of Human Endometrial Receptivity Genes. Scientific Reports, 2016, 6, art. no. 19970.

    • This work was awarded numerous prizes and led to invited talks in UK, Australia and USA, attracted international press coverage, including media interviews with The Times and The Sun. Recommended in F1000prime.


  • Gibson, D.A., Greaves, E., Critchley, H.O.D., Saunders, P.T.K. Estrogen-dependent regulation of human uterine natural killer cells promotes vascular remodelling via secretion of CCL2. Human Reproduction, 2015, 30 (6), pp. 1290-1301.

    • This was the first study to describe direct estrogen-dependent regulation of uterine NK cells and the endometrial vasculature. This studies established intra-tissue sex steroids as critical mediators of endometrial tissue remodeling in early pregnancy.


  • Cousins, F.L., Murray, A., Esnal, A., Gibson, D.A., Critchley, H.O.D., Saunders, P.T.K. Evidence from a mouse model that epithelial cell migration and mesenchymal-epithelial transition contribute to rapid restoration of uterine tissue integrity during menstruation. PLoS ONE, 2014, 9 (1), art. no. e86378. 

    • This study established a refined model of induced endometrial breakdown and repair. Using multi-colour immunofluorescent tissue staining we were able to identify novel mechanisms of tissue re-epithelialisation.

  • Gibson, D.A., Saunders, P.T.K. Endocrine disruption of oestrogen action and female reproductive tract cancers (2014) Endocrine-Related Cancer, 21 (2), pp. T13-T31.

  • Gibson, D.A., Simitsidellis, I., Collins, F., Saunders, P.T.K. Evidence of androgen action in endometrial and ovarian cancers. Endocrine-Related Cancer, 2014, 21 (4), pp. T203-T218.


  • Gibson, D.A., McInnes, K.J., Critchley, H.O.D., Saunders, P.T.K. Endometrial intracrinology - Generation of an estrogen-dominated microenvironment in the secretory phase of women. Journal of Clinical Endocrinology and Metabolism, 2013, 98 (11), pp. E1802-E1806.

    • This landmark study was the first to identify the expression of aromatase in normal endometrial function. This study and those that followed redefined the spatial and temporal regulation of endometrial function. Recommended by F1000prime.

  • Wilkens, J., Male, V., Ghazal, P., Forster, T., Gibson, D.A., Williams, A.R.W., Brito-Mutunayagam, S.L., Craigon, M., Lourenco, P., Cameron, I.T., Chwalisz, K., Moffett, A., Critchley, H.O.D. Uterine NK cells regulate endometrial bleeding in women and are suppressed by the progesterone receptor modulator asoprisnil. Journal of Immunology, 2013, 191 (5), pp. 2226-2235.


  • Gibson, D.A., Saunders, P.T.K. Estrogen dependent signaling in reproductive tissues - A role for estrogen receptors and estrogen related receptors. Molecular and Cellular Endocrinology, 2012. 348 (2), pp. 361-372.


  • Bombail, V., Gibson, D.A., Collins, F., MacPherson, S., Critchley, H.O.D., Saunders, P.T.K. A role for the orphan nuclear receptor estrogen-related receptor α in endometrial stromal cell decidualization and expression of genes implicated in energy metabolism. Journal of Clinical Endocrinology and Metabolism, 2010, 95 (10), pp. E224-E228.

  • Wallace, A.E., Gibson, D.A., Saunders, P.T.K., Jabbour, H.N. Inflammatory events in endometrial adenocarcinoma. Journal of Endocrinology, 2010, 206 (2), pp. 141-157.

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Jan 2023   I’m a title. Click to edit me.